Innovent Reports Results of Tyvyt + Byvasda (biosimilar- bevacizumab) in P-lll ORIENT-32 Study as 1L Treatment for HCC
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- The P-lll ORIENT-32 study involves assessing of Tyvyt (sintilimab) + Byvasda vs sorafenib as a 1L treatment in 571 patients in a ratio (2:1) with advanced HCC and the result were released in an oral presentation at the ESMO Asia Virtual Congress 2020
- Result: Reduction in risk of all-cause mortality (43.1%); the median OS (not reached vs 10.4 mos.); reduction in risk of progression (43.5%); m-PFS (4.6 vs 2.8 mos.)- results was presented at ESMO 2020
- The improved OS and PFS benefits of the dual regimen were generally consistent across all subgroups and showed an acceptable safety profile with no new safety signals
Ref: PRNewswire | Image: Innovent
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